Bengaluru firm, global initiative to take new compound against superbugs to patients


BENGALURU: The Global Antibiotic Research & Development Partnership (GARDP) and Bengaluru-based Bugworks Research Inc are collaborating to co-develop a promising new antibiotic compound — “BWC0977” — with broad-spectrum antibiotic exercise against multidrug-resistant micro organism that trigger life-threatening infections.
As per the settlement, GARDP will present up to $20 million to Bugworks in technical and monetary help for the pharmaceutical and scientific co-development of BWC0977.In return, Bugworks has granted GARDP manufacturing and commercialisation rights for the compound in 146 nations, nearly all of that are low-or middle-income international locations (LMICs).
“…BWC0977 has shown potent activity against two ‘critical priority’ superbugs (drug resistant pathogens) identified by the WHO – carbapenem-resistant Acinetobacter baumannii and Klebsiella pneumoniae – which are increasingly untreatable and accounted for over 20% of antimicrobial resistance (AMR)-associated deaths in 2019 according to the global research on AMR study,” the discharge learn.
Manica Balasegaram, GARDP’s government director stated “BWC0977” stands out for its novelty and potential to deal with unmet public well being wants against precedence pathogens the place few therapies exist.
Anand Anandkumar, co-founder and CEO, Bugworks, which incubated on the Centre for Cellular and Molecular Platforms (C-CAMP) in Bengaluru, stated: “An overarching goal of this partnership is to enable access to this compound simultaneously in Western countries and in LMICs with high AMR burden.
The GARDP-Bugworks collaboration builds on more than $12.4 million in prior funding from CARB-X to advance BWC0977 through early-stage research and initial clinical testing.
The release, issued by C-CAMP, reads: “The development of BWC0977 reflects the bolstering of the global health ecosystem to respond to the AMR crisis. CARB-X has provided critical support for the pre-clinical development and first-in-human (phase 1) clinical study of this compound. GARDP will now collaborate with Bugworks to further develop BWC0977 and, upon approval, enable global access.”
CARB-X R&D chief Erin Duffy, whereas stating that CARB-X was happy with its monetary and non-financial help for the Bugworks programme, stated now that this compound has been primed for superior growth, they give the impression of being ahead to GARDP’s help in bringing this potential novel, broad-spectrum antibiotic to patients.

Nilesh Desai
Nilesh Desai
The Hindu Patrika is founded in 2016 by Mr. Nilesh Desai. This website is providing news and information mainly related to Hinduism. We appreciate if you send News, information or suggestion.


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